Open Research across Disciplines

How the principles of open research can be applied to your discipline

Health Sciences and Medicine

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Case Studies

UKRN case study: Health sciences; biomedical research, specialising in endocrinology and metabolism
University of Bristol case study: Generating research impact during a pandemic: Timing matters.
University of Bristol case study: Open research practices in epidemiology.
University of Bristol case study: Bridging Gaps: Improving access to primary care with women who experience severe and multiple disadvantage. Video.
University of Bristol case study: ALSPAC’s use of data notes to promote teamwork and discoverability.  Video.
University of Newcastle case study: Supporting an open science, open source, open data approach to force field design and drug discovery with the Open Force Field Initiative
University of Sheffield case study: Ian Sudbery on Identifying gene regulatory sequences in multiple myeloma. Video
University of Suffolk case study: How My Research and Practices Support University of Suffolk Open Access and Open Science Agenda
University of Surrey case study: Using virtual representations in mHealth application interventions for health-related behaviour change
University of Surrey case study: OCTAVA: An open-source toolbox for harmonised analysis of clinical angiography images to support discovery of novel biomarkers
University of Surrey case study: Maximising the impact of patient-doctor video observation data
University of Surrey case study: Creating an internationally registered and fully accessible search strategy code for systematic reviews
University of Surrey case study: Utilising open research practices to conduct a systematic review and meta-analysis of healthcare data
University of Surrey case study: Using open research tools to uncover a new therapeutic target for an aggressive blood cancer
University of Surrey case study: Open research and systematic review on using virtual representations in mHealth application interventions for health-related behaviour change
University of Surrey case study: OCTAVA: An open-source toolbox for harmonised analysis of clinical angiography images to support discovery of novel biomarkers

Examples of open research practices

Open Methods: The “Unseating Big Pharma” case study involves collaboration from 15 countries with the aim to end the legacy of big pharma. Scientists are working together in an effort to show how an open-science model can end dependency on manufacturers and benefit vaccine equity. (Unseating big pharma: the radical plan for vaccine equity (nature.com))

Open Data: “Carsten Brink works with sensitive personal data in the field of radiotherapy for cancer patients. Having FAIR (Findable, Accessible, Interoperable, Reusable) data is essential to the researchers in his field, because they need interoperable data from a large number of patients to predict outcomes. The researchers in his field used to gather data from many different institutes and pool them in one physical location to run models. But, because they need to preserve the patients’ confidentiality, physically moving the data is a legally complicated task. Instead, they now work with distributed learning, which allows them to analyse data at other institutes without having to physically move them.”

(https://howtofair.dk/how-to-fair/#health-science)

Resources

General Resources

Open Methods

Open Data

Open Outputs

This page is adapted and extended from: Farran, E. K., Silverstein, P., Ameen, A. A., Misheva, I., & Gilmore, C. (2020, December 15). Open Research: Examples of good practice, and resources across disciplines. https://doi.org/10.31219/osf.io/3r8hb